Salivary gland neoplasms display a striking range of morphologic diversity that can confound cytologic as well as histologic interpretation. The overlapping cytologic features, the lack of markers to accurately distinguish various tumors, and the overemphasized FNA-induced histologic changes have fostered uncertainty in the role of FNA in the management of salivary gland lesions.
Despite its limitations in the classification of salivary gland neoplasms, FNA is superior to core biopsy, and its accuracy is at least comparable to frozen sections. In the hands of cytopathologists equipped with awareness of the diagnostic challenges, FNA of salivary glands is a reliable technique that can be used as a diagnostic tool or as a screening tool to triage patients into the most appropriate management scheme.
Classifying salivary gland neoplasms may be difficult, as the majority of the tumors arise from epithelial and myoepithelial cells that also have the ability to undergo a variety of metaplastic changes (squamous, mucinous, sebaceous, oncocytic, and chondroid). When a specific diagnosis cannot be made with a high level of certainty, the lesion is best reported by generating a differential diagnosis. Some experts advocate classifying salivary gland lesions into diagnostic categories based on the cell type and extracellular material.
This book, written by two experienced authors, will fulfill the need of those who wish to familiarize themselves with the FNA of salivary glands. Recognizing that the interpretation of FNA of salivary gland lesions can be fraught with challenges and pitfalls, the authors of Salivary Gland Cytopathology present a simple and practical algorithm to classify these tumors based on the overall cytomorphologic pattern of the aspirate (cellular, inflammatory, and cystic). The “cellular” category is further divided into seven subcategories, each of which is discussed in a separate chapter.
The book also provides in-depth discussions and exquisite images of the more unusual appearances and less frequently encountered neoplasms. The information is presented in a concise format, yet knowledge is imparted without sparing any detail. This book will not only serve as a basic comprehensive review but as a valuable reference to be consulted whenever diagnostic difficulties confront the reader.
Contents
1 Introduction to FNA and Salivary Gland Neoplasia
2 Salivary Gland FNA: Anatomic, Clinical, and Technical Considerations
3 Algorithmic Approach to Salivary Gland FNA: An Overview
4 The Normal Salivary Gland Aspirate
5 Inflammatory Patterns and Lymphoma
6 Matrix-Containing Tumors: Pleomorphic Adenoma and Adenoid Cystic Carcinoma
7 Basaloid Tumors: Basal Cell Adenoma and Basal Cell Adenocarcinoma
8 Oncocytic Tumors: Oncocytoma, Warthin Tumor, and Acinic Cell Carcinoma
9 Cystic and Mucinous Lesions: Mucocele and Low-Grade Mucoepidermoid Carcinoma
10 High-Grade Salivary Gland Tumors: Salivary Duct Carcinoma, High-Grade Mucoepidermoid Carcinoma, and Carcinoma ex Pleomorphic Adenoma
11. Spindle Cell Tumors: Spindled Myoepithelioma, Myoepithelial-Predominant Pleomorphic Adenoma, and Schwannoma
12. Clear Cell Neoplasms and Secondary Tumors: Epithelial-Myoepithelial Carcinoma
Index
List Price: $69.95
Despite its limitations in the classification of salivary gland neoplasms, FNA is superior to core biopsy, and its accuracy is at least comparable to frozen sections. In the hands of cytopathologists equipped with awareness of the diagnostic challenges, FNA of salivary glands is a reliable technique that can be used as a diagnostic tool or as a screening tool to triage patients into the most appropriate management scheme.
Classifying salivary gland neoplasms may be difficult, as the majority of the tumors arise from epithelial and myoepithelial cells that also have the ability to undergo a variety of metaplastic changes (squamous, mucinous, sebaceous, oncocytic, and chondroid). When a specific diagnosis cannot be made with a high level of certainty, the lesion is best reported by generating a differential diagnosis. Some experts advocate classifying salivary gland lesions into diagnostic categories based on the cell type and extracellular material.
This book, written by two experienced authors, will fulfill the need of those who wish to familiarize themselves with the FNA of salivary glands. Recognizing that the interpretation of FNA of salivary gland lesions can be fraught with challenges and pitfalls, the authors of Salivary Gland Cytopathology present a simple and practical algorithm to classify these tumors based on the overall cytomorphologic pattern of the aspirate (cellular, inflammatory, and cystic). The “cellular” category is further divided into seven subcategories, each of which is discussed in a separate chapter.
The book also provides in-depth discussions and exquisite images of the more unusual appearances and less frequently encountered neoplasms. The information is presented in a concise format, yet knowledge is imparted without sparing any detail. This book will not only serve as a basic comprehensive review but as a valuable reference to be consulted whenever diagnostic difficulties confront the reader.
Contents
1 Introduction to FNA and Salivary Gland Neoplasia
2 Salivary Gland FNA: Anatomic, Clinical, and Technical Considerations
3 Algorithmic Approach to Salivary Gland FNA: An Overview
4 The Normal Salivary Gland Aspirate
5 Inflammatory Patterns and Lymphoma
6 Matrix-Containing Tumors: Pleomorphic Adenoma and Adenoid Cystic Carcinoma
7 Basaloid Tumors: Basal Cell Adenoma and Basal Cell Adenocarcinoma
8 Oncocytic Tumors: Oncocytoma, Warthin Tumor, and Acinic Cell Carcinoma
9 Cystic and Mucinous Lesions: Mucocele and Low-Grade Mucoepidermoid Carcinoma
10 High-Grade Salivary Gland Tumors: Salivary Duct Carcinoma, High-Grade Mucoepidermoid Carcinoma, and Carcinoma ex Pleomorphic Adenoma
11. Spindle Cell Tumors: Spindled Myoepithelioma, Myoepithelial-Predominant Pleomorphic Adenoma, and Schwannoma
12. Clear Cell Neoplasms and Secondary Tumors: Epithelial-Myoepithelial Carcinoma
Index
Book Details
- Authors: William C. Faquin, Celeste Powers and M.K. Sidaway
- Paperback: 278 pages
- Publisher: Springer; 1 edition
- Language: English
- ISBN-10: 0387766227
- ISBN-13: 978-0387766225
- Product Dimensions: 7.9 x 5 x 0.3 inches
List Price: $69.95